Miss Tse has been Permanent Secretary for Environment and Ecology (Environment) (formerly named Permanent Secretary for the Environment) and Director of Environmental Protection since 17 January 2022 to oversee the operations of the Environmental Protection Department.

Miss Tse joined the Administrative Service in June 1988 and rose to the rank of Administrative Officer Staff Grade A in April 2018. She has served in various bureaux and departments. Her recent postings included Head (eHealth Record) of the Food and Health Bureau from September 2009 to December 2011, Deputy Secretary for Food and Health (Health) from January 2012 to April 2016, and Director of Home Affairs from April 2016 to January 2022.